Article on Pretreatment, Analysis, Identification and Preparation of Toxic Compounds

Pretreatment, Analysis, Identification and Preparation of Toxic Compounds Eluted in to Body Fluids from Medical and Dental Devices

Selective analysis of toxic compounds in complicated matrix such as body fluids is extremely difficult. This is because unexpected interference admixtures with almost identical retention time in chromatography may co-elute with overlapping. 1t is essential to remove admixtures byappropriate pretreatment procedures. 

Pretreatment, Analysis, Identification and Preparation of Toxic Compounds

For that purpose there may be several sorts of pretreatment methods such as liquid-liquid extraction or solid phase extraction (SPE) using column, membrane dialysis filtration ultra-filtration super fluid critical extraction SFE or adsorption using charcoal or other appropriate adsorbents. It has been reported several pretreatment methods for acidic, basic and neutral compounds in biological fluids. 

To read this article: http://scidoc.org/IJBMBS-2470-4490-01-101.php

For more details: http://scidoc.org/bioanalytical-methods-and-bioequivalence-studies.php